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INTENDED USE
The Fastect® K2/Spice Test is an immunochromatography based one
step in vitro test. It is designed for qualitative determination of synthetic
cannabis JWH-018 and JWH-073’s major metabolites in human urine
specimens at cut-off level of 50 ng/ml. This assay has not been evaluated
in the point of care location and is for forensic use only.
This assay provides only a preliminary analytical test result.
Product code MF-27 Qty. 50 per box dip test cassettes.
K2 DRUG TEST PERFORMANCE
A study was conducted by a third-party laboratory using known positive
urine from six donors. Each specimen was screened with the K2/Spice
Test. The laboratory then processed and tested each specimen following
forensic guidelines.
K2/Spice test is specific to JWH-018 pentanoic acid and JWH-073 butanoic acid
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Compounds
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Concentration
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Cross reactivity
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JWH-018 pentanoic acid
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50 ng/ml
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100%
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JWH-073 butanoic acid
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50 ng/ml
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100%
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SUMMARY AND EXPLANATION
Synthetic cannabis is a psychoactive herbal and chemical product that,
when consumed, mimics the effects of cannabis. It is best known by the
brand name K2 and Spice, both of which have largely become genericized
trademarks used for refer to any synthetic cannabis product. The studies
suggest that synthetic cannabinoid intoxication is associated with acute
psychosis, worsening of previously stable psychotic disorders, and also
may have the ability to trigger a chronic (long-term) psychotic disorder
among vulnerable individuals such as those with a family history of mental
illness. A large and complex variety of synthetic cannabinoids, most ofter
cannabicyclohexanol, JWH-018, JWH-073, or HU-210, are used. As of
March 1, 2011, five cannabinoids, JWH-018, JWH-073, CP-47, JWH-200
and cannabicyclohexanol are illegal in US because these substances have
the potential to be extremely harmful and, therefore, pose an imminent
hazard to the public safety.
- Fastect II K2/Spice
- PROCEDURE
- For Test Strip
- 1. Bring all materials and specimens to room temperature.
- 2. Remove the single test strip or device from the sealed foil pouch.
- 3. Dip the strip into the urine specimen with the arrow pointing toward
- the sample. The sample level should not be higher than the arrow pointed
- maximum line.
- 4. Hold the strip in the urine until a reddish color appears at the test area
- (approximately 20 seconds).
- 5. Withdraw the strip and place it face up on a clean, non-absorptive
- surface or leave the strip in urine if the urine level is not higher than arrow
- pointed maximum line.
- 6. Read the results at 5-10 minutes minutes after adding the sample.
- Test results may not be accurate after 10 minutes.
- INTERPRETATION OF RESULTS
- Negative: Two colored bands form. The appearance of two colored
- bands, one in test line zone and the other in control line zone, indicates
- negative results. The negative result indicates that the methylphenidate
- concentration in the specimen is either zero or less than cut-off level.
- Positive: One colored band forms. One colored band appears in control line
- zone. No colored band is found in test line zone. This is an indication that
- the methylphenidate level in the specimen is above the cut-off level.
- Invalid: If there is no colored band in control line zone, the test result is
- invalid. Retest the sample with a new device.
- Note: A borderline (+/-) in test line zone should be considered negative
- result.
- LIMITATION OF PROCEDURE
- The assay is designed for use with human urine only. A positive result with
- any of the tests indicates only the presence of a drug/metabolite and does
- not indicate or measure intoxication.
- There is a possibility that technical or procedural error as well other
- substances in certain foods and medicines may interfere with the test
- and cause false results.
Please refer “SPECIFICITY” section for lists of- substances that will produce either positive results, or that do not interfere
- with test performance. If a drug/metabolite is found present in the urine
- specimen, the assay does not indicate frequency of drug use or distinguish
- between drug of abuse and certain foods and medicines.
PERFORMANCE CHARACTERISTICS
A. Sensitivity
The cut-off concentration (sensitivity level) of K2/Spice Test is determined
to be 50 ng/ml of JWH-018 5-pentanoic acid metabolite and JWH-73
4-butanoic acid metabolite respectively.
B. Accuracy
The accuracy of the K2/Spice Test was evaluated in K2 spiked urine
specimens. Forty (40) K2 urine specimens were spiked with JWH-018
pentanoic acid or JWH-73 butanoic acid from 10 to 150 ng/ml. 30
samples with JWH-018 pentanoic acid or JWH-073 butanoic acid
concentration between 50 and 150 ng/mL were all found positive (100%
agreement ), 10 samples with JWH-018 pentanoic acid or JWH-073
butanoic acid concentration between 10 and 37.5 ng/mL were found
negative.
C. Precision
The precision study was performed by three individuals observing the
test result to determine the random error of visual interpretation. The test
results were found to have no significant differences between the three
observers.
D. Read more info on K2 Spice Incense and Bath Salts
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877-747-TEST